Liana-MCP

Natural language interface for scRNA-Seq analysis with Liana through MCP.

🪩 What can it do?

  • IO module like read and write scRNA-Seq data
  • Cell-cell communication method
  • Plotting module, circle plot, dotplot

❓ Who is this for?

  • Anyone who wants to do scRNA-Seq analysis natural language!
  • Agent developers who want to call Liana's functions for their applications

🌐 Where to use it?

You can use Liana-mcp in most AI clients, plugins, or agent frameworks that support the MCP:

  • AI clients, like Cherry Studio
  • Plugins, like Cline
  • Agent frameworks, like Agno

🎬 Demo

A demo showing scRNA-Seq cell cluster analysis in a AI client Cherry Studio using natural language based on Liana-mcp

https://github.com/user-attachments/assets/40fb5bd8-a166-4993-9979-3258ef6646a0

📚 Documentation

scmcphub's complete documentation is available at https://docs.scmcphub.org

🏎️ Quickstart

Install

Install from PyPI

pip install liana-mcp

you can test it by running

liana-mcp run

run liana-mcp locally

Refer to the following configuration in your MCP client:

check path

$ which liana 
/home/test/bin/liana-mcp
"mcpServers": {
  "liana-mcp": {
    "command": "/home/test/bin/liana-mcp",
    "args": [
      "run"
    ]
  }
}

run liana-server remotely

Refer to the following configuration in your MCP client:

run it in your server

liana-mcp run --transport shttp --port 8000

Then configure your MCP client in local AI client, like this:


"mcpServers": {
  "liana-mcp": {
    "url": "http://localhost:8000/mcp"
  }
}

🤝 Contributing

If you have any questions, welcome to submit an issue, or contact me(hsh-me@outlook.com). Contributions to the code are also welcome!

Citing

If you use liana-mcp in for your research, please consider citing following work:

Dimitrov D., Schäfer P.S.L, Farr E., Rodriguez Mier P., Lobentanzer S., Badia-i-Mompel P., Dugourd A., Tanevski J., Ramirez Flores R.O. and Saez-Rodriguez J. LIANA+ provides an all-in-one framework for cell–cell communication inference. Nat Cell Biol (2024). https://doi.org/10.1038/s41556-024-01469-w

Related in Development - Secure MCP Servers

ServerSummaryActions
BlenderMCPBlenderMCP connects Blender to Claude AI through the Model Context Protocol (MCP), allowing Claude t...View
Everything MCP ServerThis MCP server attempts to exercise all the features of the MCP protocol. It is not intended to be...View
refactor-mcpA Model Context Protocol (MCP) server that provides powerful refactoring tools for Coding Agents. It...View
Gemini Image GenerationThis is a Model Context Protocol (MCP) server that provides image generation capabilities using Goog...View
ApostropheCMSGo to WindSurf AI settings and add the following configuration to the ModelContextProtocol section:View
MCP Yeoman ServerView